The Transgender Dictionary
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Testosterone

General Information

Testosterone is a hormone often taken by trans-masculine individuals as a part of their medical transition. This masculinizing hormone can greatly alleviate gender dysphoria for those who need it.

Ways to Take T

Gel

Testosterone administered through a gel and absorbed through the skin.

Androgel is one such gel available. With the consistency of hand sanitizer, the substance is rubbed on the upper arms and absorbed through the skin within minutes. Alternative brands such as Axiron also exist.

Testosterone gel can also be administered via a nasal spray, such as with natesto.

Implants

Treatments wherin a pellet is inserted underneath the skin to administer testosterone over time are known as implants.

Testopel is an available implant for administering testosterone to the body for several months at a time.

Injections

Testosterone treatments administered by needle are known as injections.

Injections can be done either weekly or biweekly, typically using testosterone cypionate injections or testosterone enanthate. Some people go for more spaced out testosterone undecanoate injections every 10 weeks for a lower dose.

Intramuscular injections are injected straight into the muscle. They often require the help of a doctor or a family member to administer. They can be more painful than subcutaneous injections

Subcutaneous injections are injected just under the skin. They are easier to self-inject than intramuscular injections, and can be less painful.

An autoinjector known as xyosted is also available.

Oral Tablets

This is testosterone taken in pill form. Though fairly uncommon, it is still a potential administrative route. One avaliable pill is known as Jatenzo.

Topical Patches

Patches are essentially stickers via which testosterone can be absorbed through the skin.

Due to manufacturing issues, these are harder to obtain in the United States after common brands (androderm) were discontinued.

Miscellaneous Others

Some forms of testosterone are uncommon enough to only be available through compounding pharmacies. Such forms include sublingual oral troches (administered under the tongue), lozenges (medicated candy), topical cream (similar to gel but a cream), and suppositories (goes up your butt).

Some permenant changes that occur while on T.

Some non-permanent changes that occur while on T.

Hair Growth

Sometimes trans guys are unsatisfied with the hair growth provided via testosterone. This can lead to seeking out other additional routes such as minoxidil or finasteride to stimulate hair growth.

Disclaimer/Side Notes

The above lists are not all-inclusive of every possible change. Changes and timelines can vary from person to person.

Some possible side effects of going on testosterone include; weight gain, acne, sleep apnea, high blood pressure, and a risk of blood clots. When going on T, ideally, your health will be monitered reguarlly by a doctor to minimize risks.

As for what route you take T (injections, patches, etc) this will vary depending on what is avaliable where you are, or preference. Effectiveness of various routes will vary depending on the person and their body.

Testosterone is NOT birth control. It is still possible to get pregnant while on HRT. Please keep this in mind if you are sexually active, and do not rely on it to stay not pregnant.

Resources About Testosterone Hormone Therapy

bumc - Practical Guidelines for Transgender Hormone Treatment
Cleveland Clinic - Masculinizing Hormone Therapy
Folx Health - Testosterone Gel for Gender-affirming Hormone Therapy: What, Where, and How
Folx Health - Testosterone HRT and Front Hole Irritation 101: Vaginal Atrophy Symptoms and Treatment Options
Good RX - What You Need to Know About Testosterone-Based (Masculinizing) Hormone Therapy
Gender GP - HRT Timeline and Effects: Hormone Replacement Therapy Info
Hopkins Medicine - Transgender and Gender Diverse Hormone Therapy
Live Strong - Want to Start Testosterone-Based Hormone Therapy? Here's What to Know
Mayo Clinic - Masculinizing Hormone Therapy
Medical News Today - What is T therapy, and when can a person start it?
ncbi.nlm.nih.gov - Effects of testosterone treatment on transgender males: A single-institution study
Paxies - FTM Hormone Replacement Therapy: How Does HRT Work?
Planned Parenthood - Effects of Masculinizing Hormone Therapy
UCSF - Transgender Care - Information on Testosterone Hormone Therapy
Very Well Health - Testosterone for Transgender Men and Transmasculine People

Resources About Testosterone (the drug itself)

androgel
Drugs.com - AndroGel
Drugs.com - Axiron
Drugs.com - Jatenzo
Drugs.com - Natesto
Drugs.com - Testopel Pellets
Drugs.com - Testosterone Enanthate
Drugs.com - Xyosted
Health Line - Jatenzo
Health Line - Testosterone Cypionate
Hone Health - Testosterone Troches
HRT Guru - Different Types of Testosterone: Which One to Choose?
jatenzo
Mayo Clinic - Testosterone (Topical Application Route)
MedicineNet.com - Axiron vs. Androgel
natesto
tesetopel
USCF - Transgender Care - Testosterone long-acting pellets (Testopel)
Wikipedia - Testosterone Cypionate
Wikipedia - Testosterone Enanthate
Wikipedia - Testosterone Undecanoate
xyosted

YouTube Videos & Playlists

YouTube Playlist: Ashton Daniel - testosterone updates & info
YouTube Playlist: Elliot James - FTM videos
YouTube Playlist: Jackson Bird - Transition Videos
YouTube Playlist: James Roby - Transition Playlist FTM
YouTube Playlist: Jammidoger - T Changes
YouTube Playlist: Marcus Grey - FTM Transition
YouTube Playlist: NOAHFINNCE - TESTOSTERONE UPDATES
YouTube Playlist: YaBoiBenjamin - Testosterone Journey
YouTube Video: gender transition timeline ftm female-to-male - but DANCE version !
YouTube Video: FTM Singing Voice Documentation
YouTube Video: Intramuscular Self Injections (English)
YouTube Video: Intramuscular Self Injections (Spanish)
YouTube Video: Subcutaneous Self Injections (English)
YouTube Video: Subcutaneous Self Injections (Spanish)

Additional Resources

FDA approves new oral testosterone capsule for treatment of men with certain forms of hypogonadism
Planned Parenthood - HOW TO GIVE YOURSELF A HORMONE INJECTION – INTRAMUSCULAR (IM) (English)
Planned Parenthood - HOW TO GIVE YOURSELF A HORMONE INJECTION – INTRAMUSCULAR (IM) (Spanish)
Planned Parenthood - SUBCUTANEOUS (SUBQ) SELF-INJECTION VIDEO TRANSCRIPT (English)
Planned Parenthood - SUBCUTANEOUS (SUBQ) SELF-INJECTION VIDEO TRANSCRIPT (Spanish)
trans guys - DHT
Wikipedia - Finasteride
Wikipedia - Minoxidil