As a part of feminizing hormone replacement therapy, many trans-feminine people will take estrogen (often as estradiol, also spelled oestradiol). This is primarily done to relieve gender dysphoria, and replace it with gender euphoria. When someone is meant to be feminine, but their appearance is not, E is here to help!

• breast development
• body fat redistribution
• decreased libido
• decreased random erections
• softer/less oily skin
• change in body odor
• "sexual dysfunction" and genital changes such as shrinkage of the penis and testicles
• decreased sperm production (do not rely on this solely as a form of birth control)
• thinning and slowed growth of body hair (note that many people will seek out other forms of hair removal)
• experience of period symptoms, such as cramps, bloating, and other PMS symptoms
• changes in sexual pleasure

Estrogen is often taken alongside other hormones and blockers.

What is progesterone?
A hormone often taken alongside estrogen or after ending estrogen hormone therapy.

What does it do?
Taking progesterone can increase bone density, have a positive impact on sleep, decrease male pattern baldness, reduce oily skin, and increase breast growth.

What is Spironolactone?
A hormone blocker (that blocks testosterone).

bumc - Practical Guidelines for Transgender Hormone Treatment
FenwayHealth - Trans Health Injection Guide
Gender Dysphoria FYI - Estrogenic Second Puberty 101
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Gender GP - Progesterone Benefits for Trans Women in Feminisation
hemingways - info about HRT
JCEM - Progesterone Is Important for Transgender Women’s Therapy—Applying Evidence for the Benefits of Progesterone in Ciswomen
Mayo Clinic - Feminizing Hormone Therapy
MedicalNewsToday - Can trans women get periods?
modern trans hormones - subcutaneous injection of hormones
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privatemdlabs
PubMed - Hormonal Treatment of Transgender Women with Oral Estradiol
PubMed - Progesterone in gender-affirming therapy of trans women
slideshare - hormone self injection
tigermedical - Product - 1cc TuberculinSyringe
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transfemscience - Genital Application of Estradiol as a Powerful Transdermal Route for Transfeminine People
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UCSF - Trans Care - Information on Estrogen Hormone Therapy
very well health - Testosterone Blocker Options for Transgender Women
unionmedico - Self injector (for needles).
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YouTube Playlist: MTF transgender
YouTube Playlist: Transition Updates
YouTube Video: Feminizing Hormone Therapy at Seattle Children's
YouTube Video: Healthcare of the Transgender Patient (5/13/19)