S.
- Salmacian - One who wishes to have or has already obtained a mixed genital set through surgical means.
- Salphingectomy - The removal of the fallopian tubes. A common form of sterilization.
- Salpingo-Oophorectomy - The removal of both the fallopian tubes and the ovaries.
- Scrotoplasty - A type of surgery to create or repair the scrotum.
- Seahorse Dad - Refers to a transmasculine person who chooses to undergo pregnancy.
- Sex Assignment - The process by which one's biological sex is determined at birth.
- Sexuality - The quality of being sexual, especially sexual orientation and behavior.
- Sexual Orientation - The direction of a person's sexual interest.
- Shaving - A method of hair removal involving a razor.
- Slurs - Mean words.
- S.I.G. - Socially Imposed Gender (Note: This term is usually reserved for those who are intersex.)
- Social Transition - When someone changes their name, pronouns, hairstyle, and clothing to be more gender affirming in their pursuit of gender euphoria.
- Spironolactone - A testosterone blocker often taken by trans-feminine individuals as a part of HRT.
- S.R.S. - Sex Reassignment Surgery
- Stealth - When a transgender person lives and generally passes as their true gender without disclosing that they are trans. This can be done either for personal or safety reasons (or a combination of both).
- Stonewall - A riot of much historical importance.
- S.T.P. - Stand To Pee (device)
- Surgeons - Those responsible for "the surgery." Which surgery? It depends on who you ask.
- Surgical Transition - When one undergoes surgical procedures in an effort to obtain gender euphoria.
- Synthetic Hormones - Hormones with a chemical structure that differs from the natural hormones produced by the body. These are produced in a lab.